The author presents the usage of some of the major Bible quotations in the Slavonic version of De Christo et Antichristo by Hippolytus of Rome. Mainly Old Testament quotations are examined, as well as the longer ones from Revelation. Among them, there are quotes from Genesis, the Book of Isaiah and the Book of Daniel which are compared to the same places in Prophetologium (Grigorovič No. 2 / М.1685, RGB), in the so-called Catena in Prophetas (Saint-Trinity Lavra No. 89, RGB) and where possible with the commentaries of Hippolytus In Danielem, and other early Slavic translations of the Scripture as well. The quotations from Revelation are compared with some later translations of this book in order to underline their importance and usage. The lexical analysis is not the main focus of the conducted study, but it is inevitable when the quotations are compared with biblical manuscripts. Тhe main aim and scope of the article is to highlight how the biblical quotations were approached by the translator. The large-scale comparisons made show how the medieval Slavonic biblical versions vary, depending on the function of the texts translated.